Respiratory burden in obese and young asthmatics: a study of diaphragmatic kinetics.
Luís Henrique Sarmento TenórioFabiana Cavalcanti VieiraHelga Cecília Muniz de SouzaArmele de Fátima Dornelas de AndradeVirginia Maria Barros de LorenaDécio MedeirosJosé Ângelo RizzoGeorgia Veras de Araújo Gueiros LiraMarco Aurélio de Valois Correia JúniorEmanuel Sávio Cavalcanti SarinhoPublished in: Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia (2021)
The muscular hypertrophy found in the diaphragm of the obese individuals can be justified by the increase in respiratory work imposed by the chronic condition of the disease. Such increase in thickness did not occur in controlled mild asthmatics. The IL-6 and TNF-α markers detected no evidence of muscle inflammation, even though leptin was expected to be altered in obese individuals. Both obese and asthmatic patients had lower pulmonary resistance than the healthy ones.
Keyphrases
- adipose tissue
- weight loss
- metabolic syndrome
- obese patients
- type diabetes
- end stage renal disease
- bariatric surgery
- ejection fraction
- newly diagnosed
- chronic kidney disease
- oxidative stress
- rheumatoid arthritis
- pulmonary hypertension
- prognostic factors
- mechanical ventilation
- risk factors
- respiratory tract
- optical coherence tomography
- intensive care unit
- middle aged
- extracorporeal membrane oxygenation
- cystic fibrosis
- drug induced
- aqueous solution