Pharmacologically induced weight loss is associated with distinct gut microbiome changes in obese rats.
Silvia RaineriJulia A SherriffKevin S J ThompsonHuw JonesPaul T PflugerNicholas E IlottJane MellorPublished in: BMC microbiology (2022)
Sibutramine-induced weight loss in obese rats is associated with improved metabolic health, and changes to the faecal microbiome consistent with a reduction in obesity-induced bacterially-driven inflammation.
Keyphrases
- weight loss
- bariatric surgery
- high glucose
- diabetic rats
- metabolic syndrome
- roux en y gastric bypass
- type diabetes
- adipose tissue
- oxidative stress
- healthcare
- gastric bypass
- public health
- obese patients
- drug induced
- insulin resistance
- mental health
- endothelial cells
- skeletal muscle
- glycemic control
- body mass index
- human health