Subcutaneous administration, higher age and lower renal function are associated with erythrocyte methotrexate accumulation in Crohn's disease: a cross-sectional study.

Maartje M van de MeebergM L SeinenH H FidderM LinB OldenburgN K de BoerG BoumaR de JongeM Bulatović Ćalasannull null

Published in: BMC gastroenterology (2022)

MTX-PG concentrations display a considerable inter-individual variability. Higher MTX-PG accumulation is associated with subcutaneous administration, higher age, and lower renal function in Crohn's disease patients.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
physical activity
high dose
low dose
patient reported