Identification of Drugs Acting as Perpetrators in Common Drug Interactions in a Cohort of Geriatric Patients from Southern Italy and Analysis of the Gene Polymorphisms That Affect Their Interacting Potential.

Mauro Cataldi Camilla Celentano Leonardo BencivengaMichele ArcopintoChiara ResnatiAnnalaura ManesLoreta DodaniLucia ComnesRobert Vander SticheleDipak KalraGiuseppe RengoFrancesco GiallauriaUgo TramaNicola FerraraAntonio CittadiniMaurizio Taglialatela

Published in: Geriatrics (Basel, Switzerland) (2023)

We provided a list of the allelic variants influencing the activity of drug perpetrators in older adults which should be included in pharmacogenomics-oriented CDSSs to be used in geriatric medicine.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
physical activity
prognostic factors
hip fracture
adverse drug
emergency department
dna methylation
gene expression
genome wide
risk assessment