Desloratadine via its anti-inflammatory and antioxidative properties ameliorates TNBS-induced experimental colitis in rats.
Mohammad Aadil BhatSupriya RoySuneela DhaneshwarSwatantra KumarShailendra K Saxena
Published in: Immunopharmacology and immunotoxicology (2024)
DES and DES + 5-ASA demonstrated potential in alleviating colonic inflammation associated with TNBS-induced colitis in rats. The effect can be attributed to its antihistamine, anticytokine, and antioxidative properties.