Metatranscriptomic Analysis Reveals SARS-CoV-2 Mutations in Wastewater of the Frankfurt Metropolitan Area in Southern Germany.

Shelesh AgrawalLaura OrschlerSusanne Lackner

Published in: Microbiology resource announcements (2021)

We report a sequencing analysis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in wastewater samples collected in the Frankfurt metropolitan area of Germany. The majority of the detected mutations have been identified only in clinical genomes outside Frankfurt, indicating that the sequencing of SARS-CoV-2 RNA in wastewater can provide insights into emerging variants in a city.

Keyphrases

sars cov
respiratory syndrome coronavirus
wastewater treatment
anaerobic digestion
single cell
coronavirus disease
copy number
nucleic acid
gene expression
dna methylation
genome wide