Growth/differentiation factor 15 causes TGFβ-activated kinase 1-dependent muscle atrophy in pulmonary arterial hypertension.

Benjamin E GarfieldAlexi CrosbyDongmin ShaoPeiran YangCai ReadSteven SawiakStephen MooreLisa ParfittCarl HarriesMartin RiceRichard PaulMark L OrmistonNicholas W MorrellMichael I PolkeyStephen John WortPaul R Kemp

Published in: Thorax (2018)

NCT01847716; Results.

Keyphrases

pulmonary arterial hypertension
pulmonary artery
pulmonary hypertension
transforming growth factor
skeletal muscle
protein kinase
tyrosine kinase
epithelial mesenchymal transition
signaling pathway