Detecting fitness epistasis in recently admixed populations with genome-wide data.

Xumin NiMengshi ZhouHeming WangKaren Y HeUli BroeckelCraig HanisSharon KardiaSusan RedlineRichard S CooperHua TangXiaofeng Zhu

Published in: BMC genomics (2020)

Our analyses revealed two instances of fitness epistasis on chromosomes 1 and 10, and the findings suggest a potential approach to improving our understanding of adaptive evolution.

Keyphrases

genome wide
body composition
physical activity
dna methylation
electronic health record
single cell
big data
copy number
risk assessment
climate change
genetic diversity
deep learning