Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers in Acute Coronary Syndrome: Implications for Platelet Reactivity?

Maximilian TscharrePatricia P WadowskiConstantin WeikertJoseph PultarBeate EichelbergerSimon PanzerThomas Gremmel

Published in: Cardiovascular drugs and therapy (2020)

ACE inhibitors are associated with increased on-treatment residual platelet reactivity in ACS patients with potent DAPT. Further clinical trials are needed to elucidate the role of RAAS blockade with ACE inhibitors and ARBs in ACS patients treated according to current standards.

Keyphrases

angiotensin converting enzyme
acute coronary syndrome
angiotensin ii
antiplatelet therapy
clinical trial
percutaneous coronary intervention
binding protein
smoking cessation