Hypoxic Gene Signature of Primary and Metastatic Melanoma Cell Lines: Focusing on HIF-1β and NDRG-1

Mustafa Emre ErçinÖnder BozdoğanTarık ÇavuşoğluNazan BozdoğanPınar AtasoyMukadder Koçak

Published in: Balkan medical journal (2019)

Hypoxic response consists of closely related proteins in more complex pathways. These findings will shed light on hypoxic processes in melanoma and unlock a Pandora’s box for development of new therapeutic strategies.

Keyphrases

transcription factor
copy number
endothelial cells
gene expression
binding protein