Systematic genetic and proteomic screens during gametogenesis identify H2BK34 methylation as an evolutionary conserved meiotic mark.

Marion CrespoLacey J LuenseMarie ArlottoJialei HuJean DorseyEncar García-OliverParisha P ShahDelphine PfliegerShelley L BergerJérôme Govin

Published in: Epigenetics & chromatin (2020)

Our results demonstrate that a combination of genetic and proteomic approaches applied to yeast sporulation can reveal new aspects of chromatin signaling pathways during mammalian spermatogenesis.

Keyphrases

genome wide
dna methylation
copy number
signaling pathway
label free
transcription factor
gene expression
saccharomyces cerevisiae
pi k akt
oxidative stress
high throughput
cell wall