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Testosterone Propionate Promotes Proliferation and Viability of Bone Marrow Mesenchymal Stem Cells while Preserving Their Characteristics and Inducing Their Anti-Cancer Efficacy

Basak AruTuba AkdenizHüsniye DağdevirenGizem GürelGülderen Yanıkkaya Demirel
Published in: Balkan medical journal (2023)
The findings reveal that testosterone propionate promotes the proliferation and survival of bone marrow-derived mesenchymal stem cells in a dose-dependent manner without hampering their differentiation capacities, induces their polarization to the pro-inflammatory phenotype, and increases their cytotoxicity on the K562 cell line.
Keyphrases
  • bone marrow
  • signaling pathway
  • replacement therapy
  • mesenchymal stem cells
  • genome wide
  • single cell
  • dna methylation