Which cytochrome P450 metabolizes phenazepam? Step by step in silico, in vitro, and in vivo studies.
Dmitriy V IvashchenkoAnastasia V RudikAndrey A PoloznikovSergey V NikulinValeriy V SmirnovAlexander G TonevitskyEugeniy A BryunDmitriy A SychevPublished in: Drug metabolism and personalized therapy (2018)
Experimental in silico and in vivo studies confirmed that the original Russian benzodiazepine phenazepam was the substrate of CYP3A4 isoenzyme.
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