FDG-PET markers of heterogeneity and different risk of progression in amnestic MCI.

Silvia Paola CaminitiSilvia De FrancescoGiacomo TondoAlice GalliAlberto RedolfiDaniela Peraninull nullnull null

Published in: Alzheimer's & dementia : the journal of the Alzheimer's Association (2023)

Algorithm based on FDG-PET hypometabolism demonstrates distinct subtypes across aMCI; Three different subtypes show heterogeneous biological profiles and risk of progression; The cortical hypometabolism is associated with AD pathology and cognitive decline; MTL hypometabolism is associated with the lowest conversion rate and CSF-AD pathology.

Keyphrases

mild cognitive impairment
cognitive decline
pet ct
positron emission tomography
pet imaging
computed tomography
machine learning
deep learning
single cell
cerebrospinal fluid