Serum leptin levels in patients with chronic kidney disease and hypertensive heart disease: An observational cross-sectional study.

Emmanuel Kwaku OforiChristian N AdekenaVincent BoimaHenry Asare-AnaneErnest YorkeEric N Y NyarkoBismark N MohammedEmmanuel QuansahSisitha U JayasingheSeth D Amanquah

Published in: Health science reports (2023)

Patients with CKD who also had HHD reported considerably higher circulating leptin levels. Significantly higher blood leptin levels were shown to be associated with CKD stage 5 in the case group. These results are consistent with the role of leptin in the metabolic complexity seen in CKD patients. There needs to be more research into treatments that aim to lower leptin levels in CKD patients with HHD.

Keyphrases

chronic kidney disease
end stage renal disease
newly diagnosed
pulmonary hypertension