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Resolution of Pityriasis rubra pilaris induced ectropion with oral dexamethasone. A case report.

Ourania FydanakiHaytham RezqAnastasios E SepetisVarajini Joganathan
Published in: Orbit (Amsterdam, Netherlands) (2024)
An 82-year-old male presented with generalised Pityriasis rubra pilaris (PRP) managed initially by dermatology team. The patient did not respond to first- and second-line treatment, including oral acitretin, steroid creams, and methotrexate, and developed bilateral cicatricial ectropion, for which he was referred to oculoplastic team for surgical management. A head injury resulting in subacute subdural haematoma, managed with a week course of low dose oral dexamethasone, resulted in the improvement of his skin condition and complete resolution of the cicatricial ectropion within a few weeks. Thus, systemic treatment of PRP with oral dexamethasone may be considered sooner in the treatment of cicatricial ectropion in similar cases.
Keyphrases
  • low dose
  • high dose
  • clinical trial
  • oxidative stress
  • optical coherence tomography