Protein O-GlcNAcylation levels are regulated independently of dietary intake in a tissue and time-specific manner during rat postnatal development.

Thomas DupasManon DenisJustine DontaineAntoine PerselloLaurent BultotAngélique ErraudDidier VertommenBertrand BouchardArnaud TessierMatthieu RivièreJacques LebretonEdith Bigot-CorbelJérôme MontnachMichel De WaardChantal GauthierYan BurelleAaron K OlsonBertrand RozecChristine Des RosiersLuc BertrandTarik IssadBenjamin Lauzier

Published in: Acta physiologica (Oxford, England) (2020)

Our results demonstrate that protein O-GlcNAc levels are not linked to dietary intake and regulated in a time and tissue-specific manner during postnatal development. We have identified by untargeted MS putative proteins with a particular O-GlcNAc signature across the development process suggesting specific role of these proteins.

Keyphrases

mass spectrometry
preterm infants
transcription factor
multiple sclerosis
oxidative stress
ms ms
protein protein
high resolution
liquid chromatography
gas chromatography mass spectrometry
high resolution mass spectrometry
gas chromatography