Mesenchymal Stem Cell-Mediated Therapy of Peripheral Artery Disease Is Stimulated by a Lamin A-Progerin Binding Inhibitor.
Soon Chul HeoYang Woo KwonGyu Tae ParkSang-Mo KwonSun Sik BaeBum-Joon ParkJae-Ho KimPublished in: Journal of lipid and atherosclerosis (2020)
JH4 exerts anti-apoptotic effects in ASCs in conditions of oxidative stress, and contributes to the repair of ischemic hind limb injury by improving cell survival.
Keyphrases
- peripheral artery disease
- oxidative stress
- mesenchymal stem cells
- ischemia reperfusion injury
- cell death
- bone marrow
- dna damage
- cell therapy
- anti inflammatory
- induced apoptosis
- umbilical cord
- diabetic rats
- dna binding
- cerebral ischemia
- brain injury
- blood brain barrier
- replacement therapy
- smoking cessation
- subarachnoid hemorrhage
- chemotherapy induced