How does cell-based NIPT perform against chorionic villous sampling and cell-free NIPT in detecting trisomies and copy number variations? A clinical study from Denmark.

Lotte HattKatarina RavnLine Dahl JeppesenBolette Hestbek NicolaisenInga Baasch ChristensenRipudaman SinghPalle ScheldeSimon Horsholt ThomsenRikke ChristensenMarianne SindingLaura VaseMarianne OestergaardMarie Bender RuggardHanne S JensenHelle MogensenNiels UldbjergNaja BecherSara MarkholtPuk SandagerLars Henning PedersenIda Vogel

Published in: Prenatal diagnosis (2023)

Circulating trophoblasts in the maternal circulation provides the potential of screening for aneuploidies and pathogenic CNVs covering the entire fetal genome. This article is protected by copyright. All rights reserved.

Keyphrases

copy number
cell free
mitochondrial dna
genome wide
single cell
dna methylation
cell therapy
circulating tumor
human health
double blind
stem cells
gene expression
pregnant women
body mass index
bone marrow