Changes in Psychotropic Drug Blood Levels After SARS-CoV-2 Vaccination: A Two-Center Cohort Study.
Maxim KuzinFabian GardinMarkus GötschiFranziskos XepapadakosWolfram KawohlErich SeifritzAntje TrauzeddelMichael PaulzenGeorgios SchoretsanitisPublished in: Therapeutic drug monitoring (2023)
This study provides the first evidence of major changes in the plasma levels of escitalopram, fluoxetine, trazodone, and quetiapine after COVID-19 vaccination. When planning COVID-19 vaccination for patients treated with these medications, clinicians should monitor rapid changes in bioavailability and consider short-term dose adjustments to ensure safety.