Non-invasive technology for brain monitoring: definition and meaning of the principal parameters for the International PRactice On TEChnology neuro-moniToring group (I-PROTECT).
Stefano RomagnoliFrancisco A LoboEdoardo PicettiFrank A RasuloChiara RobbaBasil MattaPublished in: Journal of clinical monitoring and computing (2024)
Technologies for monitoring organ function are rapidly advancing, aiding physicians in the care of patients in both operating rooms (ORs) and intensive care units (ICUs). Some of these emerging, minimally or non-invasive technologies focus on monitoring brain function and ensuring the integrity of its physiology. Generally, the central nervous system is the least monitored system compared to others, such as the respiratory, cardiovascular, and renal systems, even though it is a primary target in most therapeutic strategies. Frequently, the effects of sedatives, hypnotics, and analgesics are entirely unpredictable, especially in critically ill patients with multiple organ failure. This unpredictability exposes them to the risks of inadequate or excessive sedation/hypnosis, potentially leading to complications and long-term negative outcomes. The International PRactice On TEChnology neuro-moniToring group (I-PROTECT), comprised of experts from various fields of clinical neuromonitoring, presents this document with the aim of reviewing and standardizing the primary non-invasive tools for brain monitoring in anesthesia and intensive care practices. The focus is particularly on standardizing the nomenclature of different parameters generated by these tools. The document addresses processed electroencephalography, continuous/quantitative electroencephalography, brain oxygenation through near-infrared spectroscopy, transcranial Doppler, and automated pupillometry. The clinical utility of the key parameters available in each of these tools is summarized and explained. This comprehensive review was conducted by a panel of experts who deliberated on the included topics until a consensus was reached. Images and tables are utilized to clarify and enhance the understanding of the clinical significance of non-invasive neuromonitoring devices within these medical settings.
Keyphrases
- quality improvement
- white matter
- resting state
- healthcare
- primary care
- intensive care unit
- deep learning
- functional connectivity
- end stage renal disease
- cerebral ischemia
- ejection fraction
- chronic kidney disease
- machine learning
- risk assessment
- high resolution
- metabolic syndrome
- optical coherence tomography
- multiple sclerosis
- extracorporeal membrane oxygenation
- physical activity
- skeletal muscle
- single cell
- cerebrospinal fluid
- climate change
- health insurance
- mass spectrometry
- convolutional neural network
- insulin resistance