A classification system for clinical relevance of somatic variants identified in molecular profiling of cancer.

Mahadeo A SukhaiKenneth J CraddockMariam ThomasAaron R HansenTong ZhangLillian SiuPhilippe BedardTracy L StockleySuzanne Kamel-Reid

Published in: Genetics in medicine : official journal of the American College of Medical Genetics (2015)

Our somatic variant classification can be of practical value to other clinical molecular laboratories performing cancer genetic profiling by promoting consistent reporting of somatic variants and permitting harmonization of variant data among laboratories and clinical studies.

Keyphrases

copy number
papillary thyroid
squamous cell
genome wide
machine learning
single cell
deep learning
childhood cancer
electronic health record
big data
young adults
artificial intelligence
drug induced