Sinonasal Adenosquamous Carcinoma - Morphology and Genetic Drivers Including Low- and High-Risk Human Papillomavirus mRNA, DEK::AFF2 Fusion, and MAML2 Rearrangement.

Dean HollidayMitra MehradKim A ElyFangjia TongXiaowei WangJen-Fan HangYing-Ju KuoJaylou M Velez-TorresAbberly Lott-LimbachJames S Lewis

Published in: Head and neck pathology (2023)

Sinonasal adenosquamous carcinoma is a somewhat heterogeneous tumor not infrequently arising ex papilloma and having various drivers including high- and low-risk HPV and rarely DEK::AFF2 fusion. The prognosis appears favorable when proper treatment is possible.

Keyphrases

high grade
genome wide
copy number
combination therapy
binding protein
dna methylation
replacement therapy