Sustained Effectiveness of Secukinumab Across Different Body Regions in Patients with Moderate-to-Severe Plaque Psoriasis from the PURE Registry.

Melinda J GooderhamKim A PappCharles LyndeIsabelle DelormeJennifer BeeckerLorne AlbrechtIgnacio Dei-CasDanielle BrassardVimal H PrajapatiAntonio VieiraLenka Rihakova

Published in: Dermatology and therapy (2022)

Overall, an early and sustained resolution of erythema, thickening, and scaling was observed. Improvements were evident across all body regions, with the most persistent disease seen in the lower limbs. Trends in disease severity, as assessed by physicians using PASI, broadly reflected the trend in the comparable questions of the Psoriasis Symptom Diary assessed by patients.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
primary care
prognostic factors
early onset
patient reported
rheumatoid arthritis
high intensity
atopic dermatitis
single molecule
drug induced