Use of liquid chromatography-tandem mass spectrometry for foscarnet quantification in human serum and cerebrospinal fluid.
Nobuyuki KatakamiNobuhiro HiramotoTakayuki IshikawaShoji FukushimaPublished in: Rapid communications in mass spectrometry : RCM (2022)
A robust LC/MS/MS method to analyze FCV was successfully developed. FCV was selectively measured using LC/MS/MS in very low extract volumes (20 μL). The method will be useful in evaluating the FCV level in human serum and CSF.