rFVIII-Fc in severe haemophilia A: The incentive switch in case of high risk of joint bleedings.

Valérie Horvais Matthieu Wargny Yohann Repessé Philippe GautierPhilippe BeurrierLaurent ArdillonBrigitte Pan-PeteschVincent CussacMarc Trossaërt

Published in: European journal of clinical investigation (2022)

The results are related to those of the pivotal clinical trials for the reduction in FVIII consumption following the switch to rFVIII-Fc, with a significant improvement in the haemorrhagic phenotype for pwSHA.

Keyphrases

clinical trial
early onset
phase ii
open label
study protocol