Fewer subsequent relapses and lower levels of IL-17 in Takayasu arteritis developed after the age of 40 years.
Shoichi FukuiNaoki IwamotoToshimasa ShimizuMasataka UmedaAyako NishinoTomohiro KogaShin-Ya KawashiriKunihiro IchinoseYasuko HiraiMami TamaiHideki NakamuraToshiyuki AramakiNozomi IwanagaYasumori IzumiTomoki OriguchiKiyoshi MigitaYukitaka UekiShuntaro SatoAtsushi KawakamiPublished in: Arthritis research & therapy (2016)
Compared to TAK ≤40, TAK >40 could be treated by lower initial doses of prednisolone to achieve remission, and with fewer relapses. These differences might be due to the difference of T helper 17 (Th17) activity suggested by the cytokine profiles.