The farming environment protects mice from allergen-induced skin contact hypersensitivity.
C P FrossardV LazarevicN GaïaS LeoC DorasW HabreJ SchrenzelD BurgerPhilippe A EigenmannPublished in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2017)
The farming environment provides a strong, allergy protective IL-22 stimulus and generates activated CD4+ T cells. Exposure to the farm environment early in their life may also provide a better protection for contact skin allergy. Whether a viral trigger might decisively influence protection for allergies remains to be determined.