Regulation of xanthine dehydrogensase gene expression and uric acid production in human airway epithelial cells.

Ryan D HuffAlan C-Y HsuKristy S NicholBernadette JonesDarryl A KnightPeter A B WarkPhilip M HansbroJeremy Alexander Hirota

Published in: PloS one (2017)

Our results suggest that the active production of uric acid from human airway epithelial cells may be intrinsically altered in asthma and be further induced by pro-inflammatory cytokines.

Keyphrases

uric acid
metabolic syndrome
gene expression
endothelial cells
induced pluripotent stem cells
chronic obstructive pulmonary disease
lung function
anti inflammatory