mTOR inhibition prevents coronary artery remodeling in a murine model of Kawasaki disease.
Angus T StockSarah ParsonsDamian B D'SilvaJacinta A HansenVarun J SharmaFiona JamesGraham StarkeyRohit D'CostaClaire L GordonIan P WicksPublished in: Arthritis & rheumatology (Hoboken, N.J.) (2022)
Our findings demonstrate that mTOR signaling contributes to coronary artery remodeling in KD, and that targeting this pathway offers a potential therapeutic strategy to prevent or restrict this pathology in high-risk KD patients. This article is protected by copyright. All rights reserved.