Fahr's syndrome associated with hypoparathyroidism: A case report.
Mukesh Kumar SarnaPallaavi GoelVarun BhargavaRishabh ParakhPublished in: The journal of the Royal College of Physicians of Edinburgh (2023)
Fahr's syndrome affects fewer than 1 in 100,000 people. It is an inherited neurological disorder, which is distinguished by atypical calcium deposition in the movement-controlling areas of brain, that is thalamus, dentate nucleus, basal ganglia, cerebellum, cerebral cortex, hippocampus and subcortical white matter. The majority of patients often experience extrapyramidal symptoms, cerebellar signs, speech difficulty, dementia and neuropsychiatric manifestations. This disease's molecular genetics have not been thoroughly investigated. Typically, young to middle-aged adults are affected though basal ganglia calcification in hypoparathyroidism is quite uncommon. Laboratory results and radiographic brain imaging helps in reaching the diagnosis. The treatment is mainly symptomatic. We present a case of Fahr's syndrome associated with hypoparathyroidism.
Keyphrases
- white matter
- middle aged
- cerebral ischemia
- end stage renal disease
- multiple sclerosis
- chronic kidney disease
- resting state
- case report
- functional connectivity
- ejection fraction
- cognitive impairment
- newly diagnosed
- mild cognitive impairment
- high resolution
- peritoneal dialysis
- depressive symptoms
- mass spectrometry
- atomic force microscopy
- deep brain stimulation
- photodynamic therapy
- physical activity
- high speed
- replacement therapy