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A mouse model of ATRX deficiency with cognitive deficits and autistic traits.

Katherine M QuesnelNicole Martin-KennyNathalie G Bérubé
Published in: Journal of neurodevelopmental disorders (2023)
Collectively, the findings indicate that early developmental abnormalities arising from ATRX deficiency in forebrain excitatory neurons contribute to the presentation of fear memory deficits as well as autistic-like behaviours.
Keyphrases
  • mouse model
  • traumatic brain injury
  • replacement therapy
  • spinal cord
  • working memory
  • case report
  • spinal cord injury
  • prefrontal cortex
  • smoking cessation