The diagnostic utility of trichorhinophalangeal syndrome type 1 immunohistochemistry for metastatic breast carcinoma in effusion cytology specimens.

Chih-Jung ChenJen-Fan HangYun-An ChenShu-Jiuan LinHung-Ming ChiuChih-Yi HsuChiung-Ru LaiChi-Shun Yang

Published in: Cancer cytopathology (2022)

TRPS1 is a sensitive and specific marker for metastatic breast cancer in serous effusion cell-block specimens. It shows superior sensitivity and specificity compared with GATA3, especially in the TNBC setting and for excluding urothelial carcinoma.

Keyphrases

metastatic breast cancer
fine needle aspiration
high grade
ultrasound guided
squamous cell carcinoma
single cell
small cell lung cancer
transcription factor
cell therapy
case report
mesenchymal stem cells
structural basis