Prevalence and long-term outcome of sub-clinical primary sclerosing cholangitis in patients with ulcerative colitis.
Emma L CulverHelen K BungayMargaret BettsColm FordeOtto BuchelCharis ManganisBryan F WarrenFraser R CummingsSatish KeshavSimon P L TravisRoger W ChapmanPublished in: Liver international : official journal of the International Association for the Study of the Liver (2021)
Prevalence of sub-clinical PSC appears high in patients with extensive UC and normal liver biochemistry, with or without CRD. Disease progression and malignancy were identified on long-term follow-up. MRC should be considered for all patients with extensive UC or CRD to stratify surveillance.