Sex-Specific Disparities in Outcomes of Transcatheter Edge-to-Edge Repair for Mitral Regurgitation: A Multicenter "Real-World" Analysis.
Felix AusbuettelSebastian BarthGeorgios ChatzisKiarash SassaniDieter FischerSebastian WeyandJulian MüllerHarald SchuettBernhard SchiefferUlrich LuesebrinkChristian WaechterPublished in: Journal of clinical medicine (2023)
female patients are older and less comorbid than males undergoing TEER. The TEER procedure is equally safe and effective in both sexes. While in-hospital mortality did not differ, female patients experienced a significantly better adjusted long-term survival compared to male patients. Concomitant AF offsets the prognostic advantage of females over males and, in contrast to males, significantly impairs long-term survival in women undergoing TEER. Further research is warranted to elucidate underlying causes for the observed sex disparities and to develop sex-tailored treatment recommendations.
Keyphrases
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- prognostic factors
- healthcare
- clinical trial
- magnetic resonance
- type diabetes
- magnetic resonance imaging
- patient reported outcomes
- pregnant women
- atrial fibrillation
- computed tomography
- skeletal muscle
- metabolic syndrome
- weight loss
- patient reported
- insulin resistance
- double blind