Model construction and drug therapy of primary ovarian insufficiency by ultrasound-guided injection.

Fangfang DaiHua LiuJuan HeJinglin WuChaoyan YuanRuiqi WangMengqin YuanDongyong YangZhimin DengLinlin WangYanqing WangXiao YangHuiling WangWei HuYan-Xiang Cheng

Published in: Stem cell research & therapy (2024)

In our study, we innovatively constructed an ultrasound-guided ovarian drug injection method to construct POI-U animal models and hUC-MSC exosomes injection. And we confirmed the therapeutic efficacy of hUC-MSC exosomes on the POI-U animal models. Our study will offer a better choice for new animal models of POI in the future and provides certain guidance for the hUC-MSCs exosome therapy in POI patients.

Keyphrases

ultrasound guided
mesenchymal stem cells
fine needle aspiration
stem cells
end stage renal disease
chronic kidney disease
newly diagnosed
emergency department
bone marrow
smoking cessation