Plasma and synovial fluid concentrations and cartilage toxicity of bupivacaine following intra-articular administration of a liposomal formulation to horses.

Heather K KnychK R MamaC E MooreAshley E HillD S McKEMIE

Published in: Equine veterinary journal (2018)

Sustained concentrations of IA bupivacaine suggest viability of this medication as an intra-articular analgesic. Effects on equine chondrocytes need further study.

Keyphrases

pain management
postoperative pain
extracellular matrix
healthcare
drug delivery
oxidative stress
neuropathic pain
spinal cord injury
adverse drug
anti inflammatory
chronic pain