Impact of controlled attenuation parameter on detecting fibrosis using liver stiffness measurement.
Thomas KarlasDavid PetroffM SassoJ-G FanY-Q MiVictor De LedinghenM KumarM Lupsor-PlatonK-H HanA C CardosoGiovanna FerraioliWah-Kheong ChanVincent Wai-Sun WongR P MyersK ChayamaM Friedrich-RustM BeaugrandF ShenJ-B HiriartShiv Kumar SarinR BadeaH W LeeP MarcellinC FiliceS MahadevaG L-H WongP CrottyK MasakiJ BojungaP BedossaV KeimJ WiegandPublished in: Alimentary pharmacology & therapeutics (2018)
Liver stiffness measurement values below aetiology-specific cut-offs are very useful for ruling out cirrhosis, and to a lesser extent for ruling out significant fibrosis. In the case of the latter, Controlled Attenuation Parameter can improve interpretation slightly. Even if cut-offs are very high, liver stiffness measurements are not very reliable for ruling in fibrosis or cirrhosis.
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