Short-course daily isoniazid and rifapentine for latent tuberculosis infection in people living with HIV who received coformulated bictegravir/emtricitabine/tenofovir alafenamide.

Bo-Huang LiouChih-Ning ChengYa-Ting LinYu-Jou LinYu-Chung ChuangKuan-Yin LinWen-Chun LiuShu-Wen LinChing-Hua KuoMing-Lung Yu Chien-Ching Hung

Published in: Journal of the International AIDS Society (2021)

BIC/FTC/TAF in combination with 1HP was well tolerated with a high completion rate. BIC trough plasma concentrations were significantly decreased with concurrent use of 1HP among PLWH with LTBI. While transient viral blips were observed during 1HP without causing subsequent treatment failure, such combination should be applied with caution.

Keyphrases

mycobacterium tuberculosis
sars cov
physical activity
antiretroviral therapy

emergency department
hiv aids
pulmonary tuberculosis
cerebral ischemia

radiation therapy
hiv infected
replacement therapy
human immunodeficiency virus

smoking cessation
adverse drug
electronic health record