A First Step to a Biomarker of Curative Surgery in Colorectal Cancer by Liquid Biopsy of Methylated Septin 9 Gene.
Miguel León-ArellanoMariano García-ArranzR RuizR OliveraS MagallaresSusana Olmedillas-LópezT Valdes-SanchezHector GuadalajaraDamián García-OlmoPublished in: Disease markers (2020)
Our study shows that circulating hypermethylated SEPT9 is a specific colorectal cancer biomarker. This hypermethylated SEPT9 DNA disappears around three months after surgery and that circulating hypermethylated SEPT9 may be the first noninvasive marker for postsurgical diagnosis; this conclusion must be confirmed with a more significant number of patients.