Impaired robust interhemispheric function integration of depressive brain from REST-meta-MDD database in China.
Ke DengJi-Hui YueJian XuPing-Ping MaXiao ChenLe LiTong-Jian BaiQi-Jing BoJun CaoGuan-Mao ChenNing-Xuan ChenWei ChenChang ChengXi-Long CuiJia DuanYi-Ru FangQi-Yong GongWen-Bin GuoZheng-Hua HouLan HuLi KuangFeng LiKai-Ming LiTao LiYan-Song LiuZhe-Ning LiuYi-Cheng LongQing-Hua LuoHua-Qing MengDai-Hui PengHai-Tang QiuJiang QiuYue-Di ShenYu-Shu ShiTian-Mei SiFei WangKai WangLi WangXiang WangYing WangXiao-Ping WuXin-Ran WuChun-Ming XieGuang-Rong XieHai-Yan XiePeng XieHong YangJian YangJia-Shu YaoShu-Qiao YaoYing-Ying YinYong-Gui YuanAi-Xia ZhangHong ZhangKe-Rang ZhangLei ZhangZhi-Jun ZhangRu-Bai ZhouYi-Ting ZhouJun-Juan ZhuChao-Jie ZouCong ZhouXi-Nian ZuoChao-Gan YanXiu-Feng XuYu-Qi ChengPublished in: Bipolar disorders (2021)
We confirmed a significant VMHC reduction in MDDs in broad areas, especially in PCC/PCu. This reduction was affected by gender, age, episode type, and illness severity. These findings suggest that the depressive brain tends to disconnect information exchange across hemispheres.