Comparison of diagnostic methods for detection of BRAFV600E mutation in ameloblastoma.

Arularasan AnbinselvamAbdul-Warith O Akinshipo Akinyele Olumuyiwa Adisa Olajumoke A EffiomXinhe ZhuKehinde E Adebiyi Godwin T Arotiba Sunday O Akintoye

Published in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology (2024)

Low-cost and less vulnerability of IHC to tissue quality make it a viable surrogate test for BRAFV600E detection in ameloblastoma. Sequential dual IHC and molecular testing for BRAFV600E will reduce equivocal results that could exclude some patients from BRAFV600E-inhibitor therapies.

Keyphrases

low cost
end stage renal disease
newly diagnosed
loop mediated isothermal amplification
chronic kidney disease
real time pcr
prognostic factors
patient reported outcomes