KLF4 Promotes Diabetic Chronic Wound Healing by Suppressing Th17 Cell Differentiation in an MDSC-Dependent Manner.

Xiong Yang Bryan J Mathis Yu Huang Wencheng Li Ying Shi

Published in: Journal of diabetes research (2021)

Our study revealed a previously unreported function of KLF4-regulated MDSCs in diabetic wound healing and identified APTO-253 as a potential agent to improve the healing of pressure ulcers.

Keyphrases

wound healing
transcription factor
type diabetes
single cell
climate change