Utility of Neoadjuvant Chemotherapy for Peritoneal Carcinomatosis Secondary to High-Grade Appendiceal Neoplasms for Patients Undergoing Cytoreductive Surgery with Hyperthermic Intraperitoneal Chemotherapy.
Christopher W MangieriOmeed MoavenCristian D ValenzuelaRichard A EraliKonstantinos I VotanopoulosPerry ShenEdward A LevinePublished in: Annals of surgical oncology (2022)
This is the largest study to evaluate high-grade appendiceal neoplasms in regard to CRS-HIPEC and NAT. NAT had no impact in regard to disease burden, cytoreduction, or recurrence patterns. Utilization of NAT was associated with decreased OS and DFS.
Keyphrases
- high grade
- low grade
- neoadjuvant chemotherapy
- locally advanced
- patients undergoing
- minimally invasive
- lymph node
- rectal cancer
- sentinel lymph node
- squamous cell carcinoma
- coronary artery bypass
- radiation therapy
- risk factors
- surgical site infection
- atrial fibrillation
- coronary artery disease
- metastatic renal cell carcinoma