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Treatment Patterns and Clinical Outcomes Among Patients with Metastatic Non-small Cell Lung Cancer Without Actionable Genomic Alterations Previously Treated with Platinum-Based Chemotherapy and Immunotherapy.

Jerome H GoldschmidtWan-Yu TsengYunfei WangJanet EspiritoAnupama VasudevanMichelle SilverJackie KwongRuchit ShahElizabeth Marrett
Published in: Drugs - real world outcomes (2024)
Among patients with metastatic non-small cell lung cancer without actionable genomic alterations previously treated with platinum + ICIs, non-platinum chemotherapy agents were most commonly prescribed in the index LOT. Clinical outcomes including time to treatment discontinuation, time to next treatment, and overall survival were short, highlighting the unmet need for more effective later-line treatments.
Keyphrases
  • small cell lung cancer
  • gene expression