Conversion of stem cells from apical papilla into endothelial cells by small molecules and growth factors.

Baicheng YiTian DingShan JiangTing GongHitesh ChopraOu ShaWaruna Lakmal DissanayakaShaohua GeCheng Fei Zhang

Published in: Stem cell research & therapy (2021)

Our study demonstrates that the set of small molecules and growth factors could significantly promote endothelial transdifferentiation of SCAP, which provides a promising candidate cell source for vascular engineering and treatment of ischemic diseases.

Keyphrases

endothelial cells
stem cells
cell therapy
single cell
ischemia reperfusion injury
vascular endothelial growth factor
combination therapy
oxidative stress
bone marrow