Specific Follicular Helper T Cell Signature in Takayasu Arteritis.

Anne Claire DesboisP RégnierV QuiniouAlexandre Le JoncourA Maciejewski-DuvalCloé ComarmondH ValletM RosenzwagG Darrasse-JèzeN DerianJ PouchotM SamsonB BienvenuP FouretF KoskasM GarridoD SèneP BrunevalPatrice CacoubD KlatzmannD Saadoun

Published in: Arthritis & rheumatology (Hoboken, N.J.) (2021)

We established the presence of a specific Tfh cell signature in both circulating and aorta-infiltrating CD4+ T cells from TAK patients. The cooperation of Tfh cells and B cells might be critical in the occurrence of vascular inflammation in patients with TAK.

Keyphrases

end stage renal disease
induced apoptosis
ejection fraction
newly diagnosed
oxidative stress
risk assessment
single cell
regulatory t cells
cell cycle arrest
stem cells
aortic valve
patient reported outcomes
mesenchymal stem cells
bone marrow
pi k akt