Copy number variation: A prognostic marker for young patients with squamous cell carcinoma of the oral tongue.

Xiaolian GuPhilip J CoatesLinda BoldrupLixiao WangAdam KrejciTed HuppRobin FahraeusLena Norberg-SpaakNicola SgaramellaTorben WilmsKarin Nylander

Published in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology (2018)

Copy number variation burden is a useful single prognostic marker for SCCOT from young, but not elderly, patients. CNV burden thus holds promise to form an important contribution when selecting suitable treatment protocols for young patients with SCCOT.

Keyphrases

copy number
mitochondrial dna
squamous cell carcinoma
genome wide
middle aged
dna methylation
risk factors
machine learning
gene expression
locally advanced
artificial intelligence