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Runs of homozygosity and testicular cancer risk.

Chey LovedayA SudK LitchfieldM LevyA HolroydP BroderickZ Kote-JaraiA M DunningK MuirJ PetoR EelesD F EastonD DudakiaN OrrN Pashayannull nullnull nullA ReidR A HuddartR S HoulstonC Turnbull
Published in: Andrology (2020)
Overall, our data do not support a major role in the risk of TGCT for recessively acting alleles acting through homozygosity, as measured by RoH in outbred populations of cases and controls.
Keyphrases
  • electronic health record
  • big data
  • germ cell
  • machine learning
  • genetic diversity
  • artificial intelligence