Re-irradiation for recurrent glioblastoma multiforme: a critical comparison of different concepts.

Andrea BaehrD TrogM OertelS WelschK KrögerO GrauerU HaverkampH T Eich

Published in: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] (2020)

Normofractionated radiotherapy is a feasible option for rGBM with a good toxicity profile. Simultaneously applied systemic therapy was associated with improved outcome. For MGMT promoter-methylated histology, higher radiation doses improved survival.

Keyphrases

radiation induced
early stage
radiation therapy
oxidative stress
transcription factor
locally advanced
squamous cell carcinoma
stem cells
free survival
bone marrow
drug induced